Development novel diagnostic agents and techniques that facilitate early detection of cancer

Research Team:  Backman, Barron, Hoffman, Huang, Kaul, Levenson, Meade, Mirkin, Pasche, Nguyen, Stupp, Perlman, Scarpulla, Soares, Wang

There is a critical need for sensitive, specific, cost effective rapid assays to identify genetic mutations associated with cancer and to characterize and validate sensitive new biomarkers that correlate with staging. Results from this Program over the last five years includes advances in cancer diagnosis in the field of imaging, where both new physical modalities and multifunctional agents are in pre-clinical studies (Backman, Hoffman, Meade, Nuygen, O'Halloran, Stupp). Members of the Cancer Genes and Molecular Targeting Program have made significant technologic advances in development of new types of diagnostic methodologies (Barron, Kaul, Levenson, Scarpulla, Mirkin) and in defined new diagnostic and prognostic markers (Soares, Kaul, Hoffman, Pasche, Huang, Wang).

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