Ken and Ruth Davee Professor in Stem Cell Biology, Neurology; Feinberg School of Medicine
Cancer Cell Biology,TRIST-Neuro Oncology/Glioblastoma
jakessler@northwestern.edu
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We have isolated cancer stem cells from more than 40 human glioblastomas, and we are studying mechanisms regualting their proliferation, survival, and differentiation. these studies focus in beta-integrin signaling with an emphasis on the interactions between foacl adhesion kinase signaling and EGF signaling. We are also examining the use of nanoengineered materials to potentially treat glioblastoma