Professor, Pediatrics; Feinberg School of Medicine
Signal Transduction in Cancer,Hematologic Malignancies
s-corey@northwestern.edu
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Bone Marrow Failure syndromes, acquired or inherited;
Neutrophil Defects;
Myeloid leukemias (acute or chronic);
Myelodysplastic Syndromes;
Myeloproliferative Syndromes;
Juvenile Myelomonocytic Leukemia (JMML);
Ataxia Telangiectasia;
Neutropenia;
Thrombocytopenia;
Systems Biology
Molecular Targeted Therapy
My laboratory studies the molecular basis for cancer and its therapy. Project 1 centers on signaling basis for leukemic cell proliferation and anti-apoptosis. Project 2 focus on cytoskeletal rearrangement as it underlies epithelial-mesenchymal transition. Project 3 targets these signaling disturbances by evaluating kinase inhibition. An overarching theme to the lab is to apply more quantitative and systems analysis to the problems of cancer and therapeutics