Professor, Medicine, Hematology Oncology Division; Feinberg School of Medicine
Cancer Cell Biology,Hematologic Malignancies
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Dr. Eklund's laboratory focuses on the molecular biology of white blood cell development, with a specific interest in abnormalities that result in myeloid leukemia. Work in the laboratory involves identification of target gene profiles for interferon regulatory transcription factors and Hox homeodomain proteins. Studies focus on understanding how interferon regulatory factors function as myeloid leukemia suppressors, and how Hox proteins function as proto-oncogenes for leukemia. The goals of these studies is to identify molecular targets for therapeutic approaches to myeloid leukemias.