The Pathology Core Facility has three main components: research histology, specimen procurement and protocol review. The research histology component provides all of the tissue processing and histology services are typically performed in a clinical laboratory, but it is specifically dedicated to the needs of the Northwestern University research community in general and the Cancer Center research community in particular. The Pathology Core Facility is unique in that it has the capability and flexibility to address specific research protocol needs. The tissue procurement component of the Pathology Core Facility has two main functions: (1) human tissue and fluid procurement, storage and distribution and (2) quality assurance and protection of research subjects. The tissue procurement component addresses the growing need for human tissue and serves as an "honest broker" with HIPAA-covered entities in an effort to expedite research activities, particularly in the use of human biological materials and associated data.
Pathology Core Facility Requisition Form and Price List: For researchers who have existing biospecimens and will be bringing them to the PathCore. Please complete prior to bringing samples and email to Adekunle Raji, Technical Director at a-raji@northwestern.edu. Please include a copy of the form with any biospecimens.
Click here to view the form.
- Pathological Analysis - Related Equipment
- Dako and Biogenix AutoStainers (3)
- Cytyc ThinPrep2000
- Leica CM1850 Cryostat
- Leica EG1140H Paraffin dispensing unit
- Leica Water baths (5; 4 dedicated)
- Leica Cover Slipper
- Light (3) and Fluorescent (1) Microscopes
- Leica cryostats (3)
- Freezer (-20C) short term storage, reagents and antibodies.
- Refrigerators (-4C) for IHC, FISH, ISH, and DNA reagents (n=2).
- ACISII Digital imaging system
- TMA instruments (2), with adapter
- Leica TP1050 Tissue processors
- Leica Rotary and Disc microtomes (4)
- Leica EG1140C Cold plate
- Leica Autostainer
- BondMax autostainer (IHC)
- Coulter Cell Counter
- Automated Slide and Cassette Labelers
- Specimen Procurement, Processing and Distribution - Related Equipment
- Laser Capture Microdissection instrument, (Arcturus Engineering, Inc.)
- MWG Biotech automated molec processor
- Bond Max cell separator for circulating tumor cells
- Refrigerated and Ambient Centrifuges
- Qiagen Automated RNA/DNA extractor
- Brinkman Eppendoff automat liquid handler
- Cytospin 3
- Freezers (-80C) (n=18)
- Research Histology
- Routine Histology embedding, sectioning and staining
- Custom Histology
- Immunohistochemistry
- In situ hybridization including FISH and CISH
- Morphologic evaluation and immunostaining scoring
- Digital imaging analysis
- Tissue microarray (TMA)
- Blood component isolation
- Laser Capture Microdissection (LCM)
- DNA/RNA extraction
- Cell monolayer generation
- Circulating tumor cells
- Others
- Specimen Procurement, Processing and Distribution
- Protocol Review
- Design
- Regulatory (IRB, etc)
Location(s):
The Pathology Core Facility is located on the 8th floor of the Olson Pavillion, 710 North Fairbanks Court, Room 8-419, Chicago Campus. Phone: 312-908-5546
Main Phone:
(312) 908-5546
Main Fax:
(312) 503-2792
Director:
Piotr Kulezsa, MD, PhD
p-kulesza@northwestern.edu
Associate Director:
Clinical Trials
Julie Karpus, MSL (ASCP)
j-karpus@northwestern.edu
312.503.1294
Technical Director:
ECOG PCO-RL
Adekunle Raji
a-raji@northwestern.edu
312.908.9595
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