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Prostate Cancer Foundation Awards $1 Million Grants to Lurie Cancer Center Led Research Teams

Two teams led by Robert H. Lurie Comprehensive Cancer Center of Northwestern University investigators will each receive $1 million from the Prostate Cancer Foundation  (PCF) to support international, multi-institutional, cross-disciplinary research with the highest potential for accelerating innovative new treatments for advanced prostate cancer.

The teams are among eight new 2017 PCF Challenge Award recipients, bringing PCF’s total investment in 2017 to $27.8 million. The following teams led by Lurie Cancer Center investigators are 2017 PCF Challenge Award recipients:   

Clinical, Environmental, Genetic and Genomic Profile of Men with Early-Onset Lethal Prostate Cancer (identifying clinical and molecular predictors of early-onset, imminently lethal prostate cancer)

Team Leaders: Maha Hussain, MD (Robert H. Lurie Comprehensive Cancer of Northwestern University), Edward Schaeffer, MD, PhD (Robert H. Lurie Comprehensive Cancer of Northwestern University), Joshua Meeks, MD, PhD (Robert H. Lurie Comprehensive Cancer of Northwestern University; Jesse Brown VA Medical Center), Roohollah Sharifi, MD (Jesse Brown VA Medical Center), Scott Tomlins MD, PhD (University of Michigan), and Philip Palmbos, MD, PhD (University of Michigan)

Targeting Chemokine Signaling and MAPK/ERK Pathway in Advanced Prostate Cancer (investigating the role of the CXCR7/MAPK/ERK pathway in castrate resistant prostate cancer and the therapeutic efficacy of targeting this pathway)

Team leaders:  Jindan Yu, MD, PhD (Robert H. Lurie Comprehensive Cancer of  Northwestern University),  Maha Hussain, MD (Robert H. Lurie Comprehensive Cancer of  Northwestern University), Peter Nelson, MD (Fred Hutchinson Cancer Research Center) and individuals from the University of Washington and the University of California, Los Angeles.

The winning teams were selected from a pool of 92 international applications following a vigorous peer review process that assessed each project’s scientific merit and potential impact to patients. As part of PCF’s commitment to accelerating innovation and supporting the career development of young investigators, the highly coveted PCF Challenge Award teams are required to include at least three investigators, one of whom must be within six years of completing a research or medical training program.

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About the Prostate Cancer Foundation 

The Prostate Cancer Foundation (PCF) is the world’s leading philanthropic organization funding and accelerating prostate cancer research.  Founded in 1993, PCF has raised more than $740 million and provided funding to more than 2,000 research programs at more than 200 cancer centers and universities.  The PCF global research enterprise extends to 19 countries and funds a robust research portfolio. PCF advocates for greater awareness of prostate cancer and more efficient investment of governmental research funds for transformational cancer research.  Its efforts have helped produce a 20-fold increase in government funding for prostate cancer.  More information about PCF can be found at


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