Elizabeth Bartom, PhD
Assistant Professor, Biochemistry and Molecular Genetics
Research Program
Cancer-Focused Research
Sequence based assays provide a key window into cellular function, informing research into mutation, transcription, and regulation. I have studied a number of important mutations in cancer genomes, including mutations in Cux1, MLL, and histone H3. In each case, I analyzed RNA-seq and/or ChIP-seq data to help characterize the cellular consequences of these mutations. This work has identified new targets for cancer therapy in leukemia and pediatric glioma. I have brought similar methods to bear in studies targeted at characterizing key developmental processes in hematopoiesis, root development, and imprinting.