Research Oversight

The Lurie Cancer Center provides oversight of all aspects of clinical research through several committees. These committees work collaboratively in this effort to provide comprehensive and robust review and monitoring oversight.

Initial Submissions

All cancer-relevant projects must be submitted in NOTIS using the electronic new protocol submission form (eNPSF). Your project will be routed for disease team review or acknowledgement (if appropriate) and then proceed to scientific review. You can access NOTIS using your NetID and password. Any questions about this process can be directed to src.ccsg@northwestern.edu.

For investigator-initiated projects, please use the templates below to complete a letter of intent (LOI) and/or your fully developed protocol. For assistance, please contact Samantha Skinner.

Documents

Letter of Intent Template (must be submitted for all interventional investigator-initiated trials prior to protocol submission)

IIT Templates (for assistance, contact Sabeeha Mukit, Monika Stankiewicz, Daphne Edgren)

Disease Teams

Provides an integrated, multidisciplinary approach to guide in the selection and prioritization of high-quality cancer research studies. Please review the Disease Team Charter for details. For questions, please contact the PRMS team at src.ccsg@northwestern.edu.

Team Leaders

Disease Team	Disease Team Leader
CCS - Pop Sci	Sofia F. Garcia, PhD
CCS - Pop Sci	Christine Rini, PhD
CP - Pop Sci	Brian Hitsman, PhD
Early Phase Therapeutics	Bilal Anouti, MD
Early Phase Therapeutics	Devalingam Mehalingam, MD
Pediatrics/LCH	Amy Walz, MD
Pediatrics/LCH	Angela Waanders, MD
TRIM - Breast	Eric Donnelly, MD
TRIM - Breast	William Gradishar, MD
TRIM - GI	Aparna Kalyan, MD
TRIM - GI	Mary Mulcahy, MD
TRIM - GU	David Vanderweele, MD, PhD
TRIM - GU	Joshua Meeks, MD, PhD
TRIM - Gynecological	Emma Barber, MD
TRIM - Head & Neck	Bharat Mittal, MD
TRIM - Head & Neck	Jochen Lorch, MD
TRIM - Head & Neck	Sandeep Samant, MD
TRIM - Leukemia	Jessica Altman, MD
TRIM - Leukemia	Shira Dinner, MD
TRIM - LPDs	Leo Gordon, MD
TRIM - LPDs	Reem Karmali, MD
TRIM - Lung	Ankit Bharat, MD
TRIM - Lung	Mohamed Abazeed, MD, PhD
TRIM - Lung	Young Chae, MD
TRIM - MPNs	Brady Stein, MD
TRIM - MPNs	Jamile Shammo, MD
TRIM - Neuro-oncology	Matthew Tate, MD
TRIM - Neuro-oncology	Priya Kumthekar, MD
TRIM - Sarcoma	Jeffrey Wayne, MD
TRIM - Sarcoma	Pedro Viveiros, MD
TRIM - Sarcoma	Seth Pollack, MD
TRIM - Skin	Jacob Choi, MD, PhD
TRIM - Skin	Sunandana Chandra, MD
TRIM - Transplant	Jayesh Mehta, MD
TRIM - Transplant	Kehinde Adekola, MD

Documents

Scientific Review Committee (SRC)

Evaluates all cancer-relevant research protocols, including the review of all protocol amendments. Please see the SRC Charter for more details.

Leadership

Name	Academic Rank	Discipline	Disease Team
Al Benson, III, MD, FACSO	Chair, Professor	Hematology/Medical Oncology	GI
Masha Kocherginsky, PhD	Co-Chair, Professor	Preventive Medicine (Biostatistics)	n/a
Priya Kumthekar, MD	Co-Chair, Professor	Neuro-Oncology & Hematology/Medical Oncology	Neuro

Voting Members

Name	Academic Rank	Discipline	Disease Team
Yasmin Abaza, MD	Assistant Professor	Hematology/Medical Oncology	Leukemia
Kehinde Adekola, MD	Associate Professor	Hematology/Medical Oncology	Transplant
Paulo Amaral, MD	Assistant Professor	Hematology/Medical Oncology	GU
Adin-Cristian Andrei, PhD	Professor	Preventative Medicine (Biostatistics)	n/a
Al Benson, III, MD, FACSO	Chair, Professor	Hematology/Medical Oncology	GI
Akhil Chawla, MD	Clinical Assistant Professor	Surgery (Surgical Oncology)	Sarcoma/GI
Jacob Choi, MD, PhD	Assistant Professor	Medical Oncology	EPT, Skin
Karan S Dixit, MD	Assistant Professor	Neuro-Oncology & Hematology/Medical Oncology	Neuro
Eric Donnelly, MD	Associate Professor	Radiation Oncology	Breast, LPDs, Gyn-Onc
William Funk, PhD	Associate Professor	Cancer Epidemiology and Prevention	Pop Sci
Andrew Gordon, MD, PhD	Assistant Professor	Radiation Oncology	n/a
Leo I Gordon, MD	Professor	Medical Oncology	LPDs
Demirkan Gursel, MD	Associate Professor	Pathology & Basic Science	n/a
Virginia Hill, MD	Associate Professor	Radiation Oncology	n/a
Olga Kantor, MD	Assistant Professor	Surgical Oncology	Breast
Irum Khan, MD	Associate Professor	Hematology/Medical Oncology	Leukemia
Masha Kocherginsky, PhD	Co-Chair, Professor	Preventive Medicine (Biostatistics)	n/a
Priya Kumthekar, MD	Co-Chair, Professor	Neuro-Oncology & Hematology/Medical Oncology	Neuro
Jin-Shei Lai, PhD	Professor	Cancer Control & Survivorship	Pop Sci
Alicia Lenzen, MD	Assistant Professor	Pediatric Hematology, Oncology, and Stem Cell Transplantation	LCH/Neuro
Adam Lin, MD, PhD	Assistant Professor	Hematology/Medical Oncology	Transplant
Robert Lewandowski, MD	Professor	Radiology (Vascular and Interventional Radiology); Hematology/Oncology; Surgery	GI
Kalvin Lung, MD	Assistant Professor	Surgical Oncology	Lung
Devalingam Mahalingam, MD	Professor	Hematology/Medical Oncology	Early Phase Therapeutics, GI
Christine Rini, PhD	Professor	Cancer Control & Survivorship	Pop Sci
Gladys Rodriguez, MD	Assistant Professor	Hematology/Medical Oncology	GI
Dario Roque, MD	Associate Professor	Gynecologic Oncology	Gyn-Onc
Ashley Ross, MD	Associate Professor	Urology	GU
Jenna Rossoff, MD	Assistant Professor	Pediatrics	LCH
Roger Stupp, MD	Professor	Neurological Surgery; Hematology/Medical Oncology, Neurology (Neuro-Oncology)	Neuro
Milkie Vu, PhD	Associate Professor	Cancer Prevention	n/a
Rebecca Williams, MD, PhD	Associate Professor	Surgical Oncology	n/a
Sun Zequn, PhD, MS	Assistant Professor	Preventative Medicine (Biostatistics)	n/a
Rotating PCF Representative	Clinical Operations Manager	Pathology	n/a
Rotating Pharmacy Representative	Research Pharmacist	Pharmacy	n/a
Rotating QA Representative	Quality Assurance Monitor	Internal QA and Monitoring	n/a
Rotating SPL representative	Clinical Operations Manager	Pathology	n/a

Administrative, Non-Voting Members

Name	Discipline	Disease Team
Ashlee Drawz, MSRC	Research Oversight and Compliance	n/a
Stephanie Hynes	Clinical Research Project Manager	Breast, EPT, LPDs, PopSci, Sarcoma
Tricia Kartcheske	Clinical Trials Administration	n/a
Meredith Lohman	PRMS Coordinator	GyneOnc, GU, H&N, Nero, Skin
Kate Nance Purcell	Senior Clinical Research Project Manager	Pediatrics/LCH
Samantha Skinner	PRMS Operations Manager	n/a
Mateo Solis Rueda	PRMS Coordinator	leukemia, transplant, lung, GI, MPNs
Ericka Chant	NCTN/PRMS Lead, Senior Clinical Research Project Manager	All Disease Teams

SRC meeting dates are typically the first Wednesday and the third Thursday of each month, with submission deadlines one week prior.

Documents

Reviewer Forms

Data and Safety Monitoring Committee (DSMC)

Responsible for data and safety monitoring, monitoring of protocol compliance.

Leadership

Name	Academic Rank	Discipline	Disease Team
David VanderWeele, MD, PhD	Chair, Associate Professor	Hematology/Medical Oncology	Genitourinary
Sonali Chaudhury, MD	Co-Chair, Associate Professor	Pediatric Hematology/Medical Oncology

Voting Members

	Name	Academic Rank	Discipline	Disease Team
*	Jessica Altman, MD	Professor	Hematology/Medical Oncology	Leukemia
*	Sunandana Chandra, MD	Associate Professor	Hematology/Medical Oncology	Skin
	Laila Gharzai, MD	Assistant Professor	Radiation Oncology, Medical Social Sciences	Head & Neck
*	Aparna Kalyan, MD	Assistant Professor	Hematology/Medical Oncology	EPT, GI
	Juliet Lumati, MD, MPH	Assistant Professor	Hematology/Medical Oncology	--
	Bushra Muneer	Pharmacist	Rotating Pharmacy Representative	--
	Ashley Plant-Fox, MD	Associate Professor	Surgical Oncology	Pediatrics
	Sean Sachdev, MD	Assistant Professor	Radiation Oncology	GU, Neuro
	Pedro A. Hermida de Viveiros, MD	Associate Professor	Radiation Oncology	Sarcoma, EPT
	Lili Zhao, PhD	Statistician	Preventative Medicine
	Steven Zhang	Pharmacist	Rotating Pharmacy Representative	--

Administrative, Non-Voting Members

	Name	Title	Discipline
	Al Benson, III, MD FACP, FACCC, FASCO	Professor Associate Director for Cooperative Groups SRC/DSMC Liaison	Hematology/Medical Oncology
	Devalingam Mahalingam, MD, PhD	Professor Director, Clinical Trials Office - Lurie Cancer Center Director, Developmental Therapeutics (DT) and DT Fellowship Program	Hematology/Medical Oncology
	Maha Hussain, MD, FACP, FASCO	Professor Deputy Director, Robert H. Lurie Comprehensive Cancer Center	Hematology/Medical Oncology
*	Carolyn Passaglia, CCRP	Administrative Director, Clinical Trials	Clinical Trials Administration
*	Ashlee Drawz, MSRC, CCRC	Director, Research Compliance and Integrity	Clinical Trials Administration
*	Patricia Kartcheske	Director, Clinical Operations Central Region	Clinical Trials Administration
*	Jennifer Mitchell	Director, Clinical Network Operations	Clinical Trials Administration
*	Leanne Fountas, MPH, CCRC	Lead Operations Manager, Study Startup & Quality Assurance	Clinical Trials Administration
*	George Koulogeorgas	Quality Assourance Operations Manager	Quality Assurance
*	Quality Assurance & Compliance Team	--	--
	Kelly Benante, MPH, CCRP	Senior Project Administrator - Chemoprevention	Chemoprevention Administration
	Chemoprevention Team	--	--

* Indicates member of Audit Sub-Committee

Documents

Revisions

All protocol revisions must receive SRC continuing review. Please submit your revision, including a summary of changes, using protocol activities in NOTIS. All investigator-initiated studies, including those initiated by another site, must be SRC approved prior to IRB submission. Industry-sponsored studies may be submitted to the SRC and IRB simultaneously. Please use the template below if the sponsor does not provide a summary of changes.

Documents

Summary of Changes Template for Investigator-Initiated Studies