Northwestern University Feinberg School of Medicine
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Cancer Epigenetics & Nuclear Dynamics Members

The Cancer Epigenetics & Nuclear Dynamics (CEND) program focuses on how nuclear dynamics and information flow within the cell are co-opted in cancer through altered genetic and epigenetic mechanisms.

Eichner, Lillian

Eichner, Lillian

Assistant Professor

Bio

The focus of the Eichner lab is to elucidate transcriptional dependencies at the intersection of epigenetics, signaling, and metabolism to reveal and harness targetable vulnerabilities in cancer. Our... [more]

Foltz, Daniel

Bio

I have consistently made essential contributions to the epigenetics field and continue to produce new paradigms of centromere specification and function. These include the identification of novel chro... [more]

Gao, Ruli

Gao, Ruli

Assistant Professor

Bio

The research projects in my lab are centered around developing and applying single cell long-read sequencing technologies and computational algorithms onto patient tumors to delineate the tumorigenic ... [more]

Gottwein, Eva

Gottwein, Eva

Associate Professor

Bio

Our research is focused on the role of viral microRNAs in herpesviral oncogenesis.

He, Yuan

He, Yuan

Associate Professor

Bio

My research program focuses on the molecular mechanisms by which large, multi-subunit complexes engage in DNA-centric processes. We are currently focusing on two major topics: (1) how gene transcripti... [more]

Ho, Karen

Ho, Karen

Associate Professor

Bio

One specific area of interest is butyrate, a short chain fatty acid produced by gut microbial fermentation of dietary fiber which is an important metabolic substrate in normal colonic epithelial cells... [more]

Huang, Sui

Huang, Sui

Associate Professor

Bio

To identify complex phenotypic markers for malignancy, we have studied the morphological distinctions in nuclear structures between normal and cancer cells. We identified the perinucleolar compartment... [more]

Ji, Peng

Ji, Peng

Professor

Bio

The research in my laboratory focuses on the studies of normal hematopoiesis and myeloid malignancies. Major research areas include: 1) Mechanistic studies of chromatin condensation during e... [more]

Ji, Zhe

Ji, Zhe

Assistant Professor

Bio

Our group use high-throughput genomic technologies and computational modeling to study the regulation of gene transcription and RNA translation underlying oncogenic processes. We aim at revealing nove... [more]

Kim, Ji-Yong Julie

Bio

In particular, my lab is interested in deciphering molecular mechanisms of progesterone receptor (PR) action in endometrial cancer and breast cancer. As PR action is context dependent, its role in the... [more]