Xiaomin Bao, PhD
Assistant Professor, Molecular Biosciences; Judd A. and Marjorie Weinberg College of Arts and Sciences
Research Program
Cancer-Focused Research
The human body is composed of various morphologically and functionally distinctive cell types, yet they all share the same genome. My group is interested in characterizing how the genome is controlled by chromatin-associated regulators to modulate spatial/temporal gene expression and to define cell identity. This is fundamental to understanding development and tissue homeostasis, and may provide new insight for human disease therapies.The primary research platform used in my group is human epidermal tissue, which integrates the strength of tissue engineering,imaging, genomics, proteomics and informatics to systematically characterize gene regulation. We are currently exploring the epigenetic regulatory mechanism underlying stem cell maintenance, tissue differentiation, as well as human diseases such as cancer.