Alfonso Mondragon, PhD
Professor, Molecular Biosciences; Judd A. and Marjorie Weinberg College of Arts and Sciences
Research Program
Cancer-Focused Research
Our laboratory is focused on understanding the relationship between atomic structure and biological function of important proteins and nucleic acids. Traditionally most structural work has been focused on obtaining atomic pictures of molecules, but biological macromolecules are dynamic and understanding their function requires the convergence of many approaches to provide information from complementary perspectives at different time and length scales. To this end, we combine a variety of structural approaches with a wide range of biophysical and biochemical techniques to understand the workings of some of the most ubiquitous molecules in the cell.