Luisa Arispe, PhD
Chair, Department of Cell and Developmental Biology
My research focuses on the signaling pathways that regulate vascular morphogenesis during development and in pathological settings. This effort that has resulted to approximately 190 peer-review publications with continued support by the NIH. A major component of our work has centered on the multiple effects of VEGF and Notch signaling in blood vessels, including their key contributions to diseases such as Alagille, CADASIL, vascular malformations and cancer. Currently our interests in the field of cancer research are on the molecular mechanisms that result on the emergence of angiosarcomas and the cross-talk between endothelial and tumor cells in the process of metastasis.