Tumor Environment & Metastasis Members
The Tumor Environment & Metastasis (TEAM) Program uses an integrative approach to elucidate key molecular interactions between tumor cells and components of the host stromal microenvironment including matrix, vascular structures and cells of the immune system.
Kiyokawa, Hiroaki
Professor
Bio
My laboratory is interested in the basic mechanisms of cell cycle control, cellular differentiation and malignant transformation, with a focus on protein regulation by ubiquitination. Our current rese... [more]
Kume, Tsutomu
Professor
Bio
For over a decade my research laboratory has focused on vascular formation and angiogenesis. A particular emphasis in my laboratory has recently been analysis of neovascularization in physiological an... [more]
LaBonne, Carole
Professor
Bio
For the past 16 years, work in my laboratory has centered on understanding the normal development of the neural crest, a stem cell population central to the evolution of the vertebrates, and at unders... [more]
Lane, Keara
Assistant Professor
Bio
Inflammation is a hallmark of cancer and primary driver of metastatic dysregulation, often mediated by activation of innate immune cells. Research in the Lane lab is focused on understanding how cell-... [more]
Lavine, Jeremy
Assistant Professor
Bio
My research interest is to understand the link between angiogenesis and inflammation in neovascular age-related macular degeneration (nAMD). Although nAMD is not an oncologic disease, the study of inf... [more]
Le Poole, Isabelle
Professor
Bio
Research in the Le Poole lab is focused on immunotherapy the etiology and treatment of vitiligo, melanoma and lymphangioleiomyomatosis (LAM) as well as tuberous sclerosis complex (TSC). Specifically, ... [more]
Liu, Huiping
Associate Professor
Bio
The Liu lab studies the molecular mechanisms underlying cancer stem cells (CSCs) and metastasis through four ongoing interactive basic and translational research projects: (1) to understand CSCs in me... [more]
Min, Booki
Professor
Bio
Foxp3+ regulatory T (Treg) cells are central regulators of immunity and tolerance. The importance of Treg cells in immunity is well demonstrated by the finding that defects in Treg cell generation or ... [more]
Misharin, Alexander
Associate Professor
Bio
I am a trained immunologist with a focus on macrophage biology. My group demonstrated that lung injury leads to accumulation and life-long persistence of monocyte-derived alveolar macrophages, which r... [more]
Miska, Jason
Assistant Professor
Bio
The goal of Dr. Miska's research is to determine how the metabolism of immune cells within glioblastoma contributes to immune suppression and tumor recurrence. Furthermore, the long-term goal of ... [more]