Biostatistics:
- Research study design
- Power/sample size
- Experimental design
- Statistical Analysis Plans
- Data collection tools
- Statistical analysis
- Variety of statistical methods
- Data visualization
- Interpretation of results
- Manuscript writing
- Clinical Trials
- Design and development
- eCRF design with PI and QAM
- Analysis and reporting
- Grant development
- Clinical trials support (IIT)
- Basic science and clinical studies
- Reproducible research pipelines
Bioinformatics:
- Raw data from NUSea or outside data
- NGSCheckMate — sample validation
- RNA-Sea
- Bulk or single cell
- Alignment, transcript quantification, differential expression, pathway analysis
- scRNA-Seq
- ChIP-Sea
- Variant Analysis
- CRISPR screen analysis
- ATAC-Sea
- Standard pipelines and new pipeline development
- CETO — modular system of sequence analysis tools and pipelines
- Study design and analysis in collaboration with Biostatistics
Clinical Informatics:
- OncoSET
- Data management: outcomes registry, biobank, raw sequence files
- Integration with Epic
- Data Capture (NOT1S/REDCap)
- Development
- Work with QAM to standardize across trial
- Analytics for LCC and CTO
- Patient recruitment to trials
- Financial tracking and dashboard
- CCSG/CoC reports
- LCC Membership DB
- NM EDW
- Clinical research data analysts
- EHR data exports
- Pathology Core
- Biobanking database
- Disburser — sample disbursing tracking
- Custom clinical databases
- Prostate, Head and Neck, Melanoma, RadOnc Breast, COVID-19 and Cancer
In addition to the co-directors, each area includes faculty and staff who will work with Lurie Cancer Center members in providing expertise as needed. Core members also engage in the following general activities:
- Collaboration with cancer center members across all programs;
- Collaboration with cancer center members on both the Chicago and Evanston campuses
- Discussion about research objectives and hypotheses;
- Writing informatics and statistical sections for grant applications;
- Active collaboration through funded grant activity;
- Active co-authoring of research findings
- Interaction and integration with other cancer center cores as needed;
- Interaction and integration but not overlapping with cores and entities external to the cancer center as needed (NUCATS, IPHAM, CPS, CDSI, BCC, NUGENE, NUSeq);
- Development of new methodology in Biostatistics and Biomedical Analytics
- Development and review of cancer related protocols;
- Education through individual contact, group seminars, journal clubs and fellow/junior faculty development;